结论：通过调整处方和工艺，可以得到体外不同时间脉冲释药的盐酸地尔硫上（艹）下（卓）片剂。

CONCLUSION:The pulsatile release of ditiazem hydrochloride could be controlled by adjusting the composition of the outer shell materials and the manipulation condition.

结论：通过调整处方和工艺，可以得到体外不同时间脉冲释药的盐酸地尔硫上（艹）下（卓）片剂。

CONCLUSION:The pulsatile release of ditiazem hydrochloride could be controlled by adjusting the composition of the outer shell materials and the manipulation condition.